|
KMID : 0359420040220020163
|
|
Korean Journal of Sports Medicine
2004 Volume.22 No. 2 p.163 ~ p.169
|
|
|
A Single Acute Eccentric Contraction Induces Rat Hamstring Muscle Strain Injury in vivo
|
|
Song Hong-Sun
Koichi Nakazato
Hiroyuki Nakajima
|
|
|
Abstract
|
|
|
|
Although strain injuries most frequently occur in hamstring muscles, these muscles have not been used as a target for the in vivo strain injury model. The hypothesis tested was whether a single acute eccentric contraction (EC) could induce rat hamstring strain injury in vivo. Male rats (n = 10) were laid sideways on a platform and secured firmly. Tetanically-activated hamstrings with percutaneous electrical stimulation were simultaneously elongated by forced extension of the knee joint. As a result, 1, 2 and 3 days after EC, the isometric tetanic force was significantly reduced in comparison with the pre-treatment control. The force had recovered at day 5. The histological examination showed the presence of fibers with abnormal oval shapes, central nuclei and active proliferation of cells. Such disturbance was most apparent in the proximal portion of hamstrings. Above all, it is suggested that an acute single EC can induce hamstrings muscle strain injury in vivo.
|
|
|
KEYWORD
|
|
|
Eccentric contraction, Animal model, Hamstrings
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|